A database of hormones and their receptors |
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HMRbase accession number | 20008 |
Swiss-prot Accession number | Q9TTM9 (Sequence in FASTA format) |
Description | Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D-adrenoreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. |
Protein Length | 571 Amino acids |
Molecular weight | 60699 |
Domain Name | 7tm_1 |
References | 1 Uhlen S., Wraith A.; "Characterization of the pig alpha-1D adrenergic receptor."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | 552898 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20025 |
Swiss-prot Accession number | Q9MZ01 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Fragment). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis (By similarity). |
Protein Length | 121 Amino acids |
Molecular weight | 13583 |
Domain Name | N/A |
References | 1 Matteri R.L.; "Sus scrofa melanin-concentrating hormone (MCH) receptor."; Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20048 |
Swiss-prot Accession number | Q95254 (Sequence in FASTA format) |
Description | Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasingpeptide receptor) (GHRP) (Ghrelin receptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Pituitary and hypothalamus. |
Post translational modification | N/A |
Function | Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). |
Protein Length | 366 Amino acids |
Molecular weight | 41195 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8688086 |
Hormone | N/A |
Gene ID | 397372 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20182 |
Swiss-prot Accession number | P79387 (Sequence in FASTA format) |
Description | Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein)(Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR5 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P-450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the Muellerian inhibiting substance (AMH) gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1/FTZF1. The SFPQ-NONO- NR5A1/SF-1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3 (By similarity). |
Protein Length | 461 Amino acids |
Molecular weight | 51613 |
Domain Name | zf-C4 Hormone_recep |
References | 1 PubMed abstract 9724033 |
Hormone | N/A |
Gene ID | 397368 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20199 |
Swiss-prot Accession number | O97716 (Sequence in FASTA format) |
Description | Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Nuclear hormone receptor. High affinity receptor for triiodothyronine. |
Protein Length | 506 Amino acids |
Molecular weight | 56265 |
Domain Name | zf-C4 Hormone_recep |
References | 1 White P., Dauncey M.J.; "Differential expression of alpha 1 and alpha 2 thyroid hormonereceptor isoforms in porcine cardiac and skeletal musclespostnatally."; Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | 397387 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20224 |
Swiss-prot Accession number | Q9GKI2 (Sequence in FASTA format) |
Description | 5-HT1F receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 366 Amino acids |
Molecular weight | 41970 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11834243 |
Hormone | N/A |
Gene ID | 397187 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20229 |
Swiss-prot Accession number | Q38PT0 (Sequence in FASTA format) |
Description | Alpha 2b adrenergic receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 446 Amino acids |
Molecular weight | 49582 |
Domain Name | 7tm_1 |
References | 1 Mehrotra S., Teunissen A.W.R.H., Saxena P.R., Sharma H.S.; "Molecular Cloning and Tissue Distribution of a Full Length cDNAEncoding Porcine Alpha 2b Adrenergic Receptor."; Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | 641353 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20330 |
Swiss-prot Accession number | P50129 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2) (5-HT2A). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. |
Protein Length | 470 Amino acids |
Molecular weight | 52676 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7794950 2 PubMed abstract 7656980 |
Hormone | N/A |
Gene ID | 397432 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20396 |
Swiss-prot Accession number | Q6Q253 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor 4 protein. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 402 Amino acids |
Molecular weight | 45013 |
Domain Name | 7tm_1 |
References | 1 Zhao W., Meng H., Pan y.; "Cloning and expression analysis of the pig 5-HT4 serotonin receptorgene."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | 397431 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20415 |
Swiss-prot Accession number | Q8SPH2 (Sequence in FASTA format) |
Description | Serotonin 5-hydroxytryptamine 7-a receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 447 Amino acids |
Molecular weight | 49677 |
Domain Name | 7tm_1 |
References | 1 Bhalla P., Saxena P.R., Sharma H.S.; "Molecular Cloning and Tissue Distribution of Porcine 5-HT7receptor."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | 397158 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20419 |
Swiss-prot Accession number | Q9GLP5 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 390 Amino acids |
Molecular weight | 43418 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11454663 |
Hormone | N/A |
Gene ID | 397563 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20420 |
Swiss-prot Accession number | Q9N263 (Sequence in FASTA format) |
Description | 5-HT1D receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 377 Amino acids |
Molecular weight | 42040 |
Domain Name | N/A |
References | 1 Bhalla P., Saxena P.R., Wurch T., Pauwels P.J., Sharma H.S.; "Molecular cloning, sequence analysis, and pharmacology of a cDNAencoding porcine 5-HT1D receptor."; Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | 397309 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20433 |
Swiss-prot Accession number | O97504 (Sequence in FASTA format) |
Description | Melanocortin receptor 4 (MC4-R). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 332 Amino acids |
Molecular weight | 36947 |
Domain Name | 7tm_1 |
References | 1 Ito Y., Minezawa M.; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 10656927 3 Matteri R.L., Dyer C.J.; Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 397359 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20445 |
Swiss-prot Accession number | Q2EF33 (Sequence in FASTA format) |
Description | MC4R. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 332 Amino acids |
Molecular weight | 36947 |
Domain Name | 7tm_1 |
References | 1 Yang X.Q., Yu H., Liu D.; "The comparative analysis on MC4R gene of wild boar, domestic pig andtheir crossbred."; Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20446 |
Swiss-prot Accession number | Q2M499 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34622 |
Domain Name | 7tm_1 |
References | 1 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20447 |
Swiss-prot Accession number | Q2M4A0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34620 |
Domain Name | 7tm_1 |
References | 1 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20448 |
Swiss-prot Accession number | Q2M4A2 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34576 |
Domain Name | 7tm_1 |
References | 1 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20449 |
Swiss-prot Accession number | Q2M4A3 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34624 |
Domain Name | 7tm_1 |
References | 1 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20453 |
Swiss-prot Accession number | Q45RC1 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34608 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16978185 2 Xu G., Ren J., Ma J., Huang L.; Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. 3 Ju Y.-T., Chang W.-H., Chu H.-P.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. 4 Du Z.Q., Vincent-Naulleau S., Gilbert H., Vignoles F.; "Detection of novel quantitative trait loci for cutaneous melanoma bygenome-wide scan in the MeLiM swine model."; Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases. 5 Geffrotin C.; Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 17150979 7 Lai F.-J., Ren J., Ai H.-S., Ding N.-S., Ma J.-W., Chen C.-Y.,Guo Y.-M., Huang L.-S.; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. 8 Xu G., Ren J., Ma J., Ding N., Guo Y., Chen C., Huang L.; Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20513 |
Swiss-prot Accession number | Q6UNS5 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 321 Amino acids |
Molecular weight | 34689 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20514 |
Swiss-prot Accession number | Q6UNS7 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 321 Amino acids |
Molecular weight | 34688 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20515 |
Swiss-prot Accession number | Q6UNS8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34620 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20516 |
Swiss-prot Accession number | Q6UNS9 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34519 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20517 |
Swiss-prot Accession number | Q6UNT0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34693 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20583 |
Swiss-prot Accession number | Q95MM8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34592 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11404341 2 Kijas J.W., Moller M., Andersson L.; Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases. 3 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases. 4 Shi K., Wang A., Li N., Deng X.M.; "Single Nucleotide Polymorphism Analysis on Melanocortin Receptor 1(MC1R) of Chinese Native Pig."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 5 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 494018 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20602 |
Swiss-prot Accession number | Q2UV90 (Sequence in FASTA format) |
Description | Putative melanin concentrating hormone receptor 2. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 339 Amino acids |
Molecular weight | 38691 |
Domain Name | 7tm_1 |
References | 1 Larsson N., Hermansson N.O., Dellsen A., Ulvsbaeck M., Schneckener S.; "Cloning of the pig Melanin concentrating hormone receptor 2(pigMCH2)."; Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 733682 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20603 |
Swiss-prot Accession number | Q5QPY1 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 353 Amino acids |
Molecular weight | 38949 |
Domain Name | 7tm_1 |
References | 1 Prestle J., Adomeit A., Hammer E., Ziehar T., Missler B., Appl T.,Schindler M.; "Cloning and functional characterization of porcine melanin-concentrating hormone receptor 1 (MCH1-R)."; Diabetologia 47:A191-A191(2004).
|
Hormone | N/A |
Gene ID | 397295 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20621 |
Swiss-prot Accession number | Q6QGW2 (Sequence in FASTA format) |
Description | GnRH II receptor 7 transmembrane. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 377 Amino acids |
Molecular weight | 41498 |
Domain Name | 7tm_1 |
References | 1 Neill J.D., Musgrove L.C., Duck L.W.; "The New GnRH Receptors: Function and Relative Role."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 414423 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20686 |
Swiss-prot Accession number | Q867C1 (Sequence in FASTA format) |
Description | Calcitonin receptor-like receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 463 Amino acids |
Molecular weight | 53787 |
Domain Name | 7tm_2 HRM |
References | 1 Kikumoto K., Katafuchi T., Minamino N.; "Specificity of porcine calcitonin receptor and calcitonin receptor-like receptor in the presence of receptor-activity-modifyingproteins."; Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 397172 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20688 |
Swiss-prot Accession number | Q8WN93 (Sequence in FASTA format) |
Description | Calcitonin receptor-like receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 462 Amino acids |
Molecular weight | 53656 |
Domain Name | N/A |
References | 1 PubMed abstract 11714898 |
Hormone | N/A |
Gene ID | 397172 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20763 |
Swiss-prot Accession number | P18871 (Sequence in FASTA format) |
Description | Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha-2AAR). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 450 Amino acids |
Molecular weight | 48976 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2170371 2 PubMed abstract 8385131 |
Hormone | N/A |
Gene ID | 399501 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20784 |
Swiss-prot Accession number | Q28998 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity (By similarity). |
Protein Length | 468 Amino acids |
Molecular weight | 50098 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9655595 2 PubMed abstract 10229356 |
Hormone | N/A |
Gene ID | 397355 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20795 |
Swiss-prot Accession number | Q28997 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 418 Amino acids |
Molecular weight | 46760 |
Domain Name | 7tm_1 |
References | 1 Liang W., Bidwell C.A., Williams S.K., Mills S.E.; "Molecular cloning of the porcine beta-2-adrenergic receptor gene."; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
2 Li W.F., Nie C., Zhou X.X., Lu P., Yao J.T., Feng J.; "Molecular cloning of the porcine beta-2-adrenergic receptor gene."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 10229356 |
Hormone | N/A |
Gene ID | 397357 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20842 |
Swiss-prot Accession number | Q95252 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | White and brown adipose tissues. |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 407 Amino acids |
Molecular weight | 43611 |
Domain Name | 7tm_1 |
References | 1 Smith T.R., Bidwell C.A., Mills S.E.; "Sus scrofa beta-3-adrenergic receptor (BAR3) gene."; Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 7592080 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20846 |
Swiss-prot Accession number | Q9TSW7 (Sequence in FASTA format) |
Description | Alpha-1A adrenergic receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 466 Amino acids |
Molecular weight | 51675 |
Domain Name | 7tm_1 |
References | 1 Uhlen S., Wraith A.; "Characterization of the pig alpha-1A adrenergic receptor."; Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 100144471 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20869 |
Swiss-prot Accession number | P32307 (Sequence in FASTA format) |
Description | Vasopressin V2 receptor (Renal-type arginine vasopressin receptor)(Antidiuretic hormone receptor) (AVPR V2). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 370 Amino acids |
Molecular weight | 40537 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8393786 2 PubMed abstract 8393786 |
Hormone | N/A |
Gene ID | 397462 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20988 |
Swiss-prot Accession number | P16582 (Sequence in FASTA format) |
Description | Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH-R) (Luteinizing hormone receptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 6 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 696 Amino acids |
Molecular weight | 78092 |
Domain Name | 7tm_1 LRR_1 |
References | 1 PubMed abstract 2502844 |
Hormone | P01219 Detail in HMRbase P01232 Detail in HMRbase |
Gene ID | 407247 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20990 |
Swiss-prot Accession number | P19756 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 638 Amino acids |
Molecular weight | 71145 |
Domain Name | N/A |
References | 1 PubMed abstract 2243805 2 PubMed abstract 8647880 |
Hormone | P01248 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20999 |
Swiss-prot Accession number | P25117 (Sequence in FASTA format) |
Description | Calcitonin receptor precursor (CT-R). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 2 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. The receptor can also couple to an additional signaling pathway via a pertussis toxin-sensitive g protein in isolated osteoclasts and in LLC-PK1 cells. |
Protein Length | 498 Amino acids |
Molecular weight | 57155 |
Domain Name | 7tm_2 HRM |
References | 1 PubMed abstract 1658940 2 PubMed abstract 8034723 3 PubMed abstract 1658940 4 PubMed abstract 8034723 |
Hormone | P01259 Detail in HMRbase |
Gene ID | 397638 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21028 |
Swiss-prot Accession number | P32306 (Sequence in FASTA format) |
Description | Oxytocin receptor (OT-R). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 386 Amino acids |
Molecular weight | 42524 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8393786 2 PubMed abstract 8393786 |
Hormone | P01177 Detail in HMRbase |
Gene ID | 397092 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21033 |
Swiss-prot Accession number | P34994 (Sequence in FASTA format) |
Description | Somatostatin receptor type 2 (SS2R) (SRIF-1). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. |
Protein Length | 369 Amino acids |
Molecular weight | 41219 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8123027 2 PubMed abstract 8123027 |
Hormone | P01168 Detail in HMRbase |
Gene ID | 497059 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21035 |
Swiss-prot Accession number | P34999 (Sequence in FASTA format) |
Description | Growth hormone-releasing hormone receptor precursor (GHRH receptor)(GRF receptor) (GRFR). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 2 family. |
Tissue Specificity | Pituitary gland. Also detected in the lymphocytes and thymocytes. |
Post translational modification | N/A |
Function | Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion. |
Protein Length | 423 Amino acids |
Molecular weight | 47200 |
Domain Name | 7tm_2 HRM |
References | 1 PubMed abstract 8413847 2 Hazem H.A., Zhang X., Smith D.P., Heiman M.L., Hsiung H.M.; Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01287 Detail in HMRbase Q9GKY5 Detail in HMRbase |
Gene ID | 397100 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21050 |
Swiss-prot Accession number | P49059 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 695 Amino acids |
Molecular weight | 78173 |
Domain Name | N/A |
References | 1 PubMed abstract 7590277 2 Wang Y.F., Meyer K.B., Schmidt K., Wan S.J., Degen S.J.F.,la Barbera A.R.; "Porcine follicle-stimulating hormone receptor."; Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 7590277 4 Wang Y.F., Meyer K.B., Schmidt K., Wan S.J., Degen S.J.F.,la Barbera A.R.; "Porcine follicle-stimulating hormone receptor."; Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01219 Detail in HMRbase P01228 Detail in HMRbase |
Gene ID | 397679 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21053 |
Swiss-prot Accession number | P49922 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R)(Luteinizing hormone-releasing hormone receptor) (LHRH). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Pituitary gland. |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 328 Amino acids |
Molecular weight | 37747 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7928774 2 PubMed abstract 11269358 |
Hormone | P49921 Detail in HMRbase |
Gene ID | 397515 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21054 |
Swiss-prot Accession number | P50133 (Sequence in FASTA format) |
Description | Parathyroid hormone/parathyroid hormone-related peptide receptorprecursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 2 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 585 Amino acids |
Molecular weight | 65682 |
Domain Name | 7tm_2 HRM |
References | 1 PubMed abstract 8688470 |
Hormone | P01269 Detail in HMRbase |
Gene ID | 397675 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21085 |
Swiss-prot Accession number | Q2Q1V0 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 5b. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 301 Amino acids |
Molecular weight | 32527 |
Domain Name | 7tm_1 |
References | 1 Duran-Prado M., Delgado E., Luque R.M., Garcia-Navarro S.,Malagon M.M., Castano J.P.; Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P01168 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21116 |
Swiss-prot Accession number | Q6JTA8 (Sequence in FASTA format) |
Description | Prolactin receptor precursor (PRL-R). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; Single-pass type I membrane protein (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 2 fibronectin type-III domains. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is a receptor for the anterior pituitary hormone prolactin (By similarity). |
Protein Length | 625 Amino acids |
Molecular weight | 69573 |
Domain Name | fn3 |
References | 1 Trott J.F., Hovey R.C.; "Cloning and characterization of multiple forms of the pig (Susscrofa) prolactin receptor."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 9321486 |
Hormone | P01238 Detail in HMRbase |
Gene ID | 414916 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21122 |
Swiss-prot Accession number | Q6YEX9 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 3. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 421 Amino acids |
Molecular weight | 45851 |
Domain Name | 7tm_1 |
References | 1 Duran-Prado M., Delgado E., Garcia-Navarro S., Castano J.P.,Malagon M.M.; "Sus scrofa somatostatin receptor subtype 3 mRNA."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P01168 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21123 |
Swiss-prot Accession number | Q6YEY1 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 5. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 40027 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16543371 |
Hormone | P01168 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21136 |
Swiss-prot Accession number | Q866U3 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 1. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 390 Amino acids |
Molecular weight | 42675 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16543371 2 Duran-Prado M., Delgado E., Garcia-Navarro S., Tostivint H.,Vaudry H., Malagon M.M., Castano J.P.; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01168 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21142 |
Swiss-prot Accession number | Q8HYN8 (Sequence in FASTA format) |
Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in skin and adrenal gland tissues. |
Post translational modification | N/A |
Function | Receptor for ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 297 Amino acids |
Molecular weight | 33283 |
Domain Name | N/A |
References | 1 PubMed abstract 12464015 2 PubMed abstract 12464015 |
Hormone | P01192 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21155 |
Swiss-prot Accession number | Q8SPP9 (Sequence in FASTA format) |
Description | Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormonereceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 8 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5) (By similarity). |
Protein Length | 764 Amino acids |
Molecular weight | 86644 |
Domain Name | 7tm_1 LRR_1 |
References | 1 PubMed abstract 12880144 2 Melen L.B., McNamara E.M., Hennen G.P., Igout A.; "Porcine thyroid stimulating hormone receptor (TSHR) mRNA variant."; Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01219 Detail in HMRbase P01224 Detail in HMRbase |
Gene ID | 397560 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21198 |
Swiss-prot Accession number | Q9TU05 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a role in the regulation of eumelanin (black/brown) and phaeomelanin (red/yellow) synthesis. |
Protein Length | 320 Amino acids |
Molecular weight | 34592 |
Domain Name | 7tm_1 |
References | 1 Cho I.C., Jung J.K., Jung Y.H., Jeon J.T.; "The complete sequence of pig (Sus scrofa) MC1R gene."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 9799269 3 Cho I.C., Jung J.K., Jung Y.H., Jeon J.T.; "The complete sequence of pig (Sus scrofa) MC1R gene."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 9799269 |
Hormone | P01192 Detail in HMRbase |
Gene ID | 494018 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21216 |
Swiss-prot Accession number | Q9GKL7 (Sequence in FASTA format) |
Description | RecName: Androgen receptor;Alternative Name: Dihydrotestosterone receptor;Alternative Name: Nuclear receptor subfamily 3 group C member 4; |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated in prostate cancer cells in response to several growth factors including EGF. Phosphorylation is induced by c-Src kinase (CSK). Tyr-511 is one of the major phosphorylation sites and an increase in phosphorylation and Src kinase activity is associated with prostate cancer progression (By similarity). |
Function | Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 (By similarity). |
Protein Length | 896 Amino acids |
Molecular weight | 97166 |
Domain Name | Androgen_recep Hormone_recep zf-C4 |
References | 1 PubMed abstract 11086548 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 397582 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21267 |
Swiss-prot Accession number | Q29040 (Sequence in FASTA format) |
Description | RecName: Estrogen receptor;ER;Alternative Name: Estradiol receptor;Alternative Name: ER-alpha;Alternative Name: Nuclear receptor subfamily 3 group A member 1; |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated by cyclin A/CDK2 (By similarity). |
Function | Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (By similarity). |
Protein Length | 595 Amino acids |
Molecular weight | 66361 |
Domain Name | Hormone_recep Oest_recep zf-C4 |
References | 1 PubMed abstract 7988744 2 PubMed abstract 8458437 3 PubMed abstract 7635163 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 397435 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21288 |
Swiss-prot Accession number | Q9XSW2 (Sequence in FASTA format) |
Description | RecName: Estrogen receptor beta;ER-beta;Alternative Name: Nuclear receptor subfamily 3 group A member 2; |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation. |
Protein Length | 526 Amino acids |
Molecular weight | 58850 |
Domain Name | Hormone_recep zf-C4 |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 396697 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21303 |
Swiss-prot Accession number | Q9N1U3 (Sequence in FASTA format) |
Description | RecName: Glucocorticoid receptor;GR;Alternative Name: Nuclear receptor subfamily 3 group C member 1; |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cytoplasm (By similarity). Nucleus (By similarity). Note=Cytoplasmic in the absence of ligand, nuclear after ligand-binding (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | Increased proteasome-mediated degradation in response to glucocorticoids (By similarity). Phosphorylated in the absence of hormone; becomes hyperphosphorylated in the presence of glucocorticoids (By similarity). Ubiquitinated; restricts glucocorticoid-mediated transcriptional signaling (By similarity). Sumoylated; this reduces transcription transactivation (By similarity). |
Function | Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation (By similarity). |
Protein Length | 782 Amino acids |
Molecular weight | 85640 |
Domain Name | GCR Hormone_recep zf-C4 |
References | 1 PubMed abstract 16421205 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 396740 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21329 |
Swiss-prot Accession number | P79404 (Sequence in FASTA format) |
Description | RecName: Mineralocorticoid receptor;MR;Alternative Name: Nuclear receptor subfamily 3 group C member 2; Fragment; |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cytoplasm (By similarity). Nucleus (By similarity). Endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Note=Cytoplasmic and nuclear in the absence of ligand; nuclear after ligand-binding. When bound to HSD11B2, it is found associated with the endoplasmic reticulum membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). |
Function | Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity). |
Protein Length | 164 Amino acids |
Molecular weight | 19695 |
Domain Name | Hormone_recep |
References | ---- |
Hormone | Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21343 |
Swiss-prot Accession number | P79386 (Sequence in FASTA format) |
Description | RecName: Nuclear receptor subfamily 0 group B member 1;Alternative Name: Nuclear receptor DAX-1; |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus (By similarity). Cytoplasm (By similarity). Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR0 subfamily. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). |
Protein Length | 471 Amino acids |
Molecular weight | 52128 |
Domain Name | Hormone_recep |
References | 1 PubMed abstract 9453240 |
Hormone | N/A |
Gene ID | 397680 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21413 |
Swiss-prot Accession number | A0P8Z4 (Sequence in FASTA format) |
Description | Nuclear receptor subfamily 6 group A member 1;Alternative Name: Germ cell nuclear factor;GCNF |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus (Probable) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR6 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity). |
Protein Length | 479 Amino acids |
Molecular weight | 54350 |
Domain Name | Hormone_recep zf-C4 |
References | 1 PubMed abstract 17416745 |
Hormone | N/A |
Gene ID | 100038028 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21431 |
Swiss-prot Accession number | O62807 (Sequence in FASTA format) |
Description | Peroxisome proliferator-activated receptor gamma;PPAR-gamma;Alternative Name: Nuclear receptor subfamily 1 group C member 3 |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | Highest expression in adipose tissue and lower in spleen. Very low levels in kidney, intestine, lung and muscle. |
Post translational modification | N/A |
Function | Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. |
Protein Length | 504 Amino acids |
Molecular weight | 57512 |
Domain Name | Hormone_recep zf-C4 |
References | 1 PubMed abstract 9931452 2 PubMed abstract 10481259 3 PubMed abstract 9731203 |
Hormone | Detail in HMRbase |
Gene ID | 397671 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21490 |
Swiss-prot Accession number | Q0GFF6 (Sequence in FASTA format) |
Description | Retinoic acid receptor RXR-gamma;Alternative Name: Retinoid X receptor gamma;Alternative Name: Nuclear receptor subfamily 2 group B member 3 |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA) (By similarity). |
Protein Length | 463 Amino acids |
Molecular weight | 50943 |
Domain Name | Hormone_recep zf-C4 |
References | 1 PubMed abstract 15389320 |
Hormone | N/A |
Gene ID | 445465 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21508 |
Swiss-prot Accession number | A3RGC1 (Sequence in FASTA format) |
Description | Vitamin D3 receptor;VDR;Alternative Name: 1,25-dihydroxyvitamin D3 receptor;Alternative Name: Nuclear receptor subfamily 1 group I member 1 |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Plays a central role in calcium homeostasis (By similarity). |
Protein Length | 427 Amino acids |
Molecular weight | 48128 |
Domain Name | Hormone_recep zf-C4 |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 396628 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21557 |
Swiss-prot Accession number | Q5RLR7 (Sequence in FASTA format) |
Description | Nuclear receptor subfamily 4 group A member 2; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 40 Amino acids |
Molecular weight | 4642 |
Domain Name | N/A |
References | 1 PubMed abstract 16573537 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21763 |
Swiss-prot Accession number | O18762 (Sequence in FASTA format) |
Description | Steroidogenic factor-1; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 64 Amino acids |
Molecular weight | 7321 |
Domain Name | Hormone_recep |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21851 |
Swiss-prot Accession number | O46402 (Sequence in FASTA format) |
Description | Estrogen receptor alpha; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 159 Amino acids |
Molecular weight | 18464 |
Domain Name | Hormone_recep |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21916 |
Swiss-prot Accession number | O97726 (Sequence in FASTA format) |
Description | Neuron-derived orphan receptor-1 alfa |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 643 Amino acids |
Molecular weight | 70078 |
Domain Name | Hormone_recep zf-C4 |
References | ---- |
Hormone | N/A |
Gene ID | 397479 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21917 |
Swiss-prot Accession number | O97727 (Sequence in FASTA format) |
Description | Neuron-derived orphan receptor-1 beta |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 446 Amino acids |
Molecular weight | 47716 |
Domain Name | zf-C4 |
References | ---- |
Hormone | N/A |
Gene ID | 100151854 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21923 |
Swiss-prot Accession number | O97895 (Sequence in FASTA format) |
Description | Retinoic acid receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 136 Amino acids |
Molecular weight | 15526 |
Domain Name | Hormone_recep zf-C4 |
References | 1 PubMed abstract 10481259 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21927 |
Swiss-prot Accession number | P79297 (Sequence in FASTA format) |
Description | Retinoic acid receptor beta; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 141 Amino acids |
Molecular weight | 15880 |
Domain Name | Hormone_recep |
References | 1 PubMed abstract 9241041 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21928 |
Swiss-prot Accession number | P79298 (Sequence in FASTA format) |
Description | Retinoic acid receptor alpha; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 130 Amino acids |
Molecular weight | 15198 |
Domain Name | zf-C4 |
References | 1 PubMed abstract 9241041 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21929 |
Swiss-prot Accession number | P79300 (Sequence in FASTA format) |
Description | Retinoic acid receptor gamma; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 224 Amino acids |
Molecular weight | 25306 |
Domain Name | Hormone_recep |
References | 1 PubMed abstract 9241041 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22001 |
Swiss-prot Accession number | Q28981 (Sequence in FASTA format) |
Description | Glucocorticoid receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 53 Amino acids |
Molecular weight | 5425 |
Domain Name | GCR |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22002 |
Swiss-prot Accession number | Q29398 (Sequence in FASTA format) |
Description | Progesterone receptor protein; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 117 Amino acids |
Molecular weight | 13493 |
Domain Name | Hormone_recep |
References | 1 PubMed abstract 1714838 |
Hormone | Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22094 |
Swiss-prot Accession number | Q6EEU2 (Sequence in FASTA format) |
Description | Peroxisome proliferator activated receptor alpha; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 30 Amino acids |
Molecular weight | 3182 |
Domain Name | zf-C4 |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22168 |
Swiss-prot Accession number | Q6Q6S5 (Sequence in FASTA format) |
Description | Testicular progesterone receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 214 Amino acids |
Molecular weight | 24853 |
Domain Name | Hormone_recep |
References | ---- |
Hormone | Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22203 |
Swiss-prot Accession number | Q6UQ07 (Sequence in FASTA format) |
Description | Peroxisome proliferator activated receptor alpha; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 33 Amino acids |
Molecular weight | 3932 |
Domain Name | zf-C4 |
References | 1 PubMed abstract 14687083 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22204 |
Swiss-prot Accession number | Q6UZD7 (Sequence in FASTA format) |
Description | Estrogen receptor 2; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 45 Amino acids |
Molecular weight | 5261 |
Domain Name | Hormone_recep |
References | 1 PubMed abstract 15147399 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22227 |
Swiss-prot Accession number | Q71V40 (Sequence in FASTA format) |
Description | Estrogen receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 138 Amino acids |
Molecular weight | 15676 |
Domain Name | Hormone_recep |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22228 |
Swiss-prot Accession number | Q71V41 (Sequence in FASTA format) |
Description | Estrogen receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 150 Amino acids |
Molecular weight | 15901 |
Domain Name | Oest_recep |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22229 |
Swiss-prot Accession number | Q71V72 (Sequence in FASTA format) |
Description | Orphan nuclear receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 80 Amino acids |
Molecular weight | 9216 |
Domain Name | Hormone_recep |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22355 |
Swiss-prot Accession number | Q866Q2 (Sequence in FASTA format) |
Description | Peroxisome proliferator-activated receptor delta |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 441 Amino acids |
Molecular weight | 49773 |
Domain Name | Hormone_recep zf-C4 |
References | ---- |
Hormone | Detail in HMRbase |
Gene ID | 397297 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22428 |
Swiss-prot Accession number | Q8HY51 (Sequence in FASTA format) |
Description | Nuclear oxysterol receptor LxR-alpha; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 95 Amino acids |
Molecular weight | 11012 |
Domain Name | zf-C4 |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22511 |
Swiss-prot Accession number | Q8SQ00 (Sequence in FASTA format) |
Description | Pregnane X receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 330 Amino acids |
Molecular weight | 38099 |
Domain Name | Hormone_recep |
References | 1 PubMed abstract 11981033 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22696 |
Swiss-prot Accession number | Q9BE98 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 232 Amino acids |
Molecular weight | 24554 |
Domain Name | Androgen_recep |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22735 |
Swiss-prot Accession number | Q9GKJ1 (Sequence in FASTA format) |
Description | Retinoic acid receptor beta; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 42 Amino acids |
Molecular weight | 4972 |
Domain Name | N/A |
References | 1 PubMed abstract 11528129 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22814 |
Swiss-prot Accession number | Q9MZG4 (Sequence in FASTA format) |
Description | Peroxisome proliferator activated receptor beta; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 441 Amino acids |
Molecular weight | 49820 |
Domain Name | Hormone_recep zf-C4 |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22817 |
Swiss-prot Accession number | Q9N0K2 (Sequence in FASTA format) |
Description | Estradiol receptor beta; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 87 Amino acids |
Molecular weight | 10185 |
Domain Name | Hormone_recep |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22818 |
Swiss-prot Accession number | Q9N0K3 (Sequence in FASTA format) |
Description | Progesterone receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 132 Amino acids |
Molecular weight | 15033 |
Domain Name | Hormone_recep |
References | ---- |
Hormone | Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22821 |
Swiss-prot Accession number | Q9N135 (Sequence in FASTA format) |
Description | Peroxisome proliferator activated receptor alpha; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 468 Amino acids |
Molecular weight | 52013 |
Domain Name | Hormone_recep zf-C4 |
References | 1 PubMed abstract 11483366 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22869 |
Swiss-prot Accession number | Q9TTA2 (Sequence in FASTA format) |
Description | Peroxisome proliferator activated receptor alpha; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 171 Amino acids |
Molecular weight | 18778 |
Domain Name | zf-C4 |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22918 |
Swiss-prot Accession number | Q9XS80 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 31 Amino acids |
Molecular weight | 3733 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22923 |
Swiss-prot Accession number | Q9XSN0 (Sequence in FASTA format) |
Description | Thyroid hormone receptor beta 1 (C-erbA-beta 1); Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 203 Amino acids |
Molecular weight | 23577 |
Domain Name | zf-C4 |
References | 1 PubMed abstract 10514561 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22956 |
Swiss-prot Accession number | O02671 (Sequence in FASTA format) |
Description | Leptin receptor;LEP-R;Alternative Name: OB receptor;OB-R;Alternative Name: CD_antigen=CD295;Precursor |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; Single-pass type I membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 2 subfamily. Contains 4 fibronectin type-III domains. |
Tissue Specificity | Kidney, liver, spleen, lung, brain, testis, uterus, ovary, corpus luteum, theca and granulosa cells. |
Post translational modification | On ligand binding, phosphorylated on two conserved C-terminal tyrosine residues by JAK2. Tyr-986 is required for complete binding and activation of PTPN11, ERK/FOS activation and, for interaction with SOCS3. Phosphorylation on Tyr-1141 is required for STAT3 binding/activation (By similarity). |
Function | Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3 (By similarity). Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity). |
Protein Length | 1165 Amino acids |
Molecular weight | 132523 |
Domain Name | fn3 Lep_receptor_Ig |
References | 1 PubMed abstract 10911396 2 PubMed abstract 9800339 3 PubMed abstract 9069130 |
Hormone | Q29406 Detail in HMRbase |
Gene ID | 396836 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |